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Medical Edge Newspaper Column from Mayo Clinic

SURGERY, THERAPY COULD RELIEVE CHILD’S TORMENT OVER ‘HARELIP’

DEAR MAYO CLINIC: My grandson is 6 years old and suffers terribly from teasing now that he’s at school, and frustration because he talks funny. His problem is that he was born with a harelip and my daughter hasn’t done anything about it. Can’t they fix that so his looks and his talking are more normal? — West Virginia

ANSWER: “Cleft lip” is now the preferred term for the malformation you describe. It can occur by itself as a split in the upper lip, or in conjunction with a cleft, or split, in the roof of the mouth. This combined condition is known as “cleft palate.”

In this condition, the lip or palate doesn’t fuse properly during fetal development. The cleft can range from a small indentation in the upper lip (hence the older term “harelip,” likening the appearance to that of a rabbit’s natural upper lip shape) to a segment missing from the upper lip.

The crevice can extend into the nose and the roof of the mouth, causing problems with breathing and eating. If the malformation is severe, other medical problems can occur — from problems with feeding and weight gain in infants, to delayed speech development and chronic ear infections, to self-consciousness about cosmetic flaws.

From your description, it sounds as if your grandson is suffering from speech impairment and cosmetic concerns. Both can be remedied with the help of skilled medical professionals: surgeons who specialize in head and face reconstruction, and speech therapists who can teach the child to control his tongue, mouth and air passages to make the common sounds of speech.

For a mild malformation, a single surgery may be sufficient. More severe malformations usually require multiple surgeries over several years.

Encourage your daughter to seek an evaluation from an experienced medical/surgical/speech-therapy team. It can make a profound difference in how your grandson feels about himself and how others respond to him — especially during these early years, when the foundations of self-esteem are being built.

Oren Friedman, M.D., Otorhinolaryngology, Mayo Clinic, Rochester, Minn.

Additional Resources:
Treatment of Cleft Lip
Appointment Information
More Information on Cleft Lip


DEAR MAYO CLINIC: I have been devastated several times in my life by deaths of friends to malignant melanoma. Now I just learned a woman I work with has it, and it has spread to the brain. The doctors here say there’s nothing to be done. She has two toddlers, and I can’t stand to sit by and just watch her die. Isn’t there some surgery or something that could be tried? — East Peoria, Ill.

ANSWER: Patients who have malignant melanoma that has spread to the brain have a poor prognosis, and treatment can be difficult because the disease progresses so quickly. However, a review of the medical literature and our experience confirms that if the spread involves only one tumor location, surgery might be beneficial — especially if the cancer is not spreading throughout the body. Because we don’t know the details of your friend’s condition, we can’t say definitively if this is an option for her.

Stereotactic radiosurgery is another choice when the spread is confined to one or a few sites. This is an advanced, noninvasive therapy that uses various devices to deliver a precise, high dose of radiation to a defined target. Because it is an outpatient procedure done under local anesthesia, it requires no recovery time. Stereotactic radiosurgery is both safe and effective, and an attractive option for select patients.

External beam whole-brain radiation therapy may be another option for your friend. While this form of radiation can relieve symptoms, it is unlikely to completely eradicate melanoma that has spread to the brain.

Cancer-killing drugs — chemotherapy — are another possibility. New therapeutic agents may enable drugs to work directly on cancer cells in the brain.

In the future, the most effective treatment approach to this highly lethal cancer will likely involve a combination of several effective therapies. Because there is so much research activity focused on this form of cancer, we encourage you to continue to help your friend search for treatment options.

Robert McWilliams, M.D., and Svetomir Markovic, M.D., Ph.D., Oncology and Hematology, Mayo Clinic, Rochester, Minn.

Additional Resources:
Treatment of Melanoma
Appointment Information
More Information on Melanoma

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